Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282287 | 0.89 | NPC1 (0.58) | ALDH1A1KMT2AMEN1NPC1POLB | |
| SCHEMBL7278994 | 0.86 | SMN1; SMN2 (0.73) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL27935848 | 0.86 | MEN1 (0.61) | ALDH1A1KMT2AMEN1POLBKDM4E | |
| SCHEMBL5751507 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL793647 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1NPC1POLB | |
| SCHEMBL7279123 | 0.85 | KHK (0.53) | ALDH1A1KMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL7288853 | 0.85 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1GFERSMN1; SMN2 | |
| SCHEMBL10210776 | 0.85 | NPC1 (0.74) | ALDH1A1KMT2AMEN1TSHRNPC1 | |
| Hydrochloric Acid SCHEMBL210978 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1NPC1POLB | |
| SCHEMBL13102889 | 0.84 | SMN1; SMN2 (0.79) | ALDH1A1KMT2AMEN1GFERTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |