SCHEMBL7278729

SCHEMBL7278729

CS(=O)(=O)OCC1CCC1COS(C)(=O)=O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.42
TSHR P16473 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MMP9 P14780 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7278734 1.00 USP2 (0.42) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL14559618 1.00 USP2 (0.42) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL2548198 0.90 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL931109 0.90 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL927049 0.90 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL7273258 0.90 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4144733 0.90 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4829843 0.90 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL14268316 0.90 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL17688155 0.90 KDM4E (0.39) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5780632-A Imide derivatives and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0464846-B1 Imide derivatives, and their production and use SUMITOMO PHARMA (JP) 1998-04-22 EP disclosed
EP-0464846-A1 Imide derivatives, and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1992-01-08 EP disclosed