SCHEMBL7273258

SCHEMBL7273258

CS(=O)(=O)OC[C@H]1CCCC[C@@H]1COS(C)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MMP9 P14780 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4829843 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL17688155 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL2548198 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL14268316 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL924034 1.00 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL931109 0.95 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL4144733 0.95 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL927049 0.95 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL12908138 0.92 KDM4E (0.33) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL12238524 0.92 KDM4E (0.33) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10426770-B2 Process for the preparation of Lurasidone hydrochloride Jubilant Generics Limited (IN) 2019-10-01 US disclosed
US-20170246165-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LURASIDONE HYDROCHLORIDE Jubilant Generics Limited (IN) 2017-08-31 US disclosed
WO-2013132511-A1 NOVEL POLYMORPH OF LURASIDONE HYDROCHLORIDE HETERO RESEARCH FOUNDATION (IN) 2013-09-12 WO disclosed
WO-2011162562-A2 [6+5] FUSED BICYCLES AS A THROMBIN ANTAGONIST, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE BICYCLES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2011-12-29 WO disclosed
US-5780632-A Imide derivatives and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0464846-B1 Imide derivatives, and their production and use SUMITOMO PHARMA (JP) 1998-04-22 EP disclosed
US-5532372-A Imide derivatives, and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) 1996-07-02 US disclosed
EP-0464846-A1 Imide derivatives, and their production and use SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1992-01-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170246165-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF LURASIDONE HYDROCHLORIDE FFAR3, FAR1, PRLHR KDM4E 3240/4885USP2 3603/4885ALDH1A1 479/4885
US-10426770-B2 Process for the preparation of Lurasidone hydrochloride FFAR3, REN, LSS KDM4E 3399/4885USP2 3569/4885ALDH1A1 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.