Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278732 | 1.00 | KMT2A (0.35) | KMT2AL3MBTL1MAPTNPSR1TSHR | |
| SCHEMBL9238883 | 0.77 | KMT2A (0.34) | KMT2AL3MBTL1MAPTNPSR1TSHR | |
| SCHEMBL9238889 | 0.77 | KMT2A (0.34) | KMT2AL3MBTL1MAPTNPSR1TSHR | |
| SCHEMBL9848597 | 0.77 | KMT2A (0.38) | KMT2AL3MBTL1MAPTNPSR1TSHR | |
| SCHEMBL9848598 | 0.77 | KMT2A (0.38) | KMT2AL3MBTL1MAPTNPSR1TSHR | |
| SCHEMBL9848559 | 0.70 | KMT2A (0.42) | KMT2AL3MBTL1MAPTNPSR1TSHR | |
| SCHEMBL9848563 | 0.70 | KMT2A (0.42) | KMT2AL3MBTL1MAPTNPSR1TSHR | |
| SCHEMBL7273016 | 0.68 | KMT2A (0.40) | KMT2AL3MBTL1MAPTNPSR1MAPK1 | |
| SCHEMBL7273008 | 0.68 | KMT2A (0.40) | KMT2AL3MBTL1MAPTNPSR1MAPK1 | |
| SCHEMBL11133814 | 0.66 | KMT2A (0.47) | KMT2AL3MBTL1MAPTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679645-A1 | Pharmacologically active CNS pyridmidin compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-11-02 | — | — | EP | disclosed |
| EP-0459819-A2 | Pharmacologically active CNS compound | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |