Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848563 | 1.00 | KMT2A (0.42) | KMT2ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9848597 | 0.81 | KMT2A (0.38) | KMT2ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9848598 | 0.81 | KMT2A (0.38) | KMT2ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11133816 | 0.74 | KMT2A (0.47) | KMT2ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11133814 | 0.74 | KMT2A (0.47) | KMT2ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11655430 | 0.72 | ALDH1A1 (0.36) | KMT2ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9238883 | 0.72 | KMT2A (0.34) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL9238889 | 0.72 | KMT2A (0.34) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1MAPT | |
| SCHEMBL7273293 | 0.71 | KMT2A (0.49) | KMT2ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7273288 | 0.71 | KMT2A (0.49) | KMT2ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459829-A1 | Pharmacologically active CNS compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |