Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278775 | 1.00 | NR5A1 (0.45) | NR5A1PLA2G4BTP53TSHRS1PR1 | |
| SCHEMBL7271288 | 0.93 | ALOX12 (0.44) | PLA2G4BTP53TSHRS1PR1S1PR5 | |
| SCHEMBL7271292 | 0.93 | ALOX12 (0.44) | PLA2G4BTP53TSHRS1PR1S1PR5 | |
| SCHEMBL7282536 | 0.85 | TP53 (0.48) | PLA2G4BTP53TSHRRARB | |
| SCHEMBL7282538 | 0.85 | TP53 (0.48) | PLA2G4BTP53TSHRRARB | |
| SCHEMBL7280292 | 0.82 | NR5A1 (0.56) | NR5A1PLA2G4BTP53TSHRLTA4H | |
| SCHEMBL7280293 | 0.82 | NR5A1 (0.56) | NR5A1PLA2G4BTP53TSHRLTA4H | |
| SCHEMBL7278956 | 0.77 | S1PR5 (0.43) | NR5A1PLA2G4BTP53TSHRS1PR1 | |
| SCHEMBL7278957 | 0.77 | S1PR5 (0.43) | NR5A1PLA2G4BTP53TSHRS1PR1 | |
| SCHEMBL3683047 | 0.76 | TP53 (0.57) | PLA2G4BTP53TSHRRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1638-H | CYCLIC HEXAPEPTIDE | FURUTA TAKAHISA (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0462531-B1 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0729974-A1 | Cyclic polypeptide with antibiotic activity and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5376634-A | Microbiocides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0486011-A2 | Pharmaceutical composition against Pneumocystis carinii | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0462531-A2 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |