Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270546 | 0.82 | ESR2 (0.46) | ESR2ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL1628 | 0.79 | ESR2 (0.43) | ESR2ALDH1A1HPGDPTPN5MAPK1 | |
| SCHEMBL2686 | 0.79 | ESR2 (0.40) | ESR2ALDH1A1PTPN5GRIA2GRIA4 | |
| SCHEMBL17120715 | 0.77 | ESR2 (0.59) | ESR2ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL28799873 | 0.76 | ESR2 (0.54) | ESR2ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL17120710 | 0.73 | ESR2 (0.54) | ESR2ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL31410710 | 0.71 | ESR2 (0.76) | ESR2ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL17120717 | 0.71 | ESR2 (0.51) | ESR2ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL24838568 | 0.71 | ESR2 (0.59) | ESR2ALDH1A1CYP1A2CYP3A4HSD17B10 | |
| SCHEMBL16484546 | 0.71 | ESR2 (0.59) | ESR2ALDH1A1CYP1A2CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |