Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 3/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270546 | 0.87 | ESR2 (0.46) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL2686 | 0.81 | ESR2 (0.40) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL7279558 | 0.79 | ESR2 (0.46) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL3008 | 0.78 | LTB4R2 (0.50) | MMEFFAR1AKR1B1OXTRAVPR1A | |
| SCHEMBL1629 | 0.77 | MYC (0.45) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL2104 | 0.77 | NLRP3 (0.43) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL14496801 | 0.74 | TDP1 (0.42) | MAPK1SMN1; SMN2GAAALDH1A1HPGD | |
| SCHEMBL2870 | 0.74 | MYC (0.47) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL2132 | 0.74 | MYC (0.47) | ESR2MMEFFAR1AKR1B1PTPN5 | |
| SCHEMBL14998792 | 0.74 | AGTR1 (0.44) | ESR2MMEFFAR1AKR1B1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |