⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29829475 | 0.98 | PDE10A (0.95) | — | |
| SCHEMBL9634611 | 0.98 | PDE10A (0.95) | — | |
| Sulfuric Acid SCHEMBL8146392 | 0.85 | PDE10A (0.72) | — | |
| Diethyl Sulfide SCHEMBL27760941 | 0.85 | PDE10A (0.72) | — | |
| SCHEMBL4956973 | 0.74 | PDE10A (0.55) | — | |
| SCHEMBL717559 | 0.72 | — | — | |
| SCHEMBL7975635 | 0.72 | — | — | |
| SCHEMBL4526132 | 0.70 | — | — | |
| SCHEMBL17406617 | 0.65 | — | — | |
| SCHEMBL1553537 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2841 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | claimed |
| EP-4568972-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | claimed |
| CN-120118077-A | Compound and application thereof | 润尔眼科药物（广州）有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-119654326-A | Novel heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2025-03-18 | — | — | CN | claimed |
| WO-2024226914-A2 | MRGPRX2 ANTAGONISTS AND METHODS OF USE THEREOF | SEPTERNA, INC. (US) | 2024-10-31 | — | — | WO | claimed |
| CN-118215664-A | Substituted triazoloheteroaryl compounds as USP1 inhibitors and uses thereof | 上海瑛派药业有限公司 | 2024-06-18 | — | — | CN | claimed |
| WO-2024033277-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | claimed |
| EP-4299576-A1 | [1,2,4]-TRIAZOLO[A]PYRIMIDINE DERIVATIVES AS THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) EMITTERS AND PROCESS OF PREPARATION THEREOF | Vilnius University (LT) | 2024-01-03 | — | — | EP | claimed |
| US-11851432-B2 | Triazolopyrimidine compounds and their use in treating cancer | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-12-26 | — | — | US | claimed |
| US-20230183237-A1 | COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | claimed |
| US-4968595-A | CCONTROLLED SO THAT DEVELOPMENT STARTS AT CORNERS OR EDGES OF GRAINS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-11-06 | — | — | US | claimed |
| WO-1990001030-A1 | SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-08 | — | — | WO | claimed |
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | claimed |
| CN-85103646-A | Make the method for novel triazolo pyrimidine | — | 1986-11-19 | — | — | CN | claimed |
| EP-0101517-B1 | NOVEL S-TRIAZOLE(1,5-A)PYRIMIDINE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-29 | — | — | EP | claimed |
| EP-0178029-A2 | Detergent compositions containing compatible organic emetic agent | THE PROCTER & GAMBLE COMPANY (US) | 1986-04-16 | — | — | EP | claimed |
| EP-0101517-A1 | NOVEL s-TRIAZOLE(1,5-a)PYRIMIDINE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-29 | — | — | EP | claimed |
| US-4397943-A | POLYMERIC 1,2,4-TRIAZOLO-1,5-A-PYRIMIDINES AS STABILIZERS | FUJI PHOTO FILM CO., LTD. (JP) | 1983-08-09 | — | — | US | claimed |
| US-4269820-A | MIXTURE WITH TOXIC HERBICIDES, PESTICIDES AND INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-26 | — | — | US | claimed |
| US-3960568-A | Photographic material containing fine silver halide particles and hydroxylamino substituted triazine or pyrimidine sensitizers | FUJI PHOTO FILM CO., LTD. (JA) | 1976-06-01 | — | — | US | claimed |