⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975635 | 1.00 | — | — | |
| SCHEMBL72796 | 0.72 | — | — | |
| SCHEMBL17406617 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL29829475 | 0.70 | PDE10A (0.95) | — | |
| SCHEMBL9634611 | 0.70 | PDE10A (0.95) | — | |
| SCHEMBL6201153 | 0.67 | PDE10A (0.36) | — | |
| SCHEMBL746705 | 0.65 | — | — | |
| SCHEMBL23176291 | 0.64 | PDE10A (0.33) | — | |
| SCHEMBL17227450 | 0.64 | PDE10A (0.33) | — | |
| SCHEMBL4511531 | 0.64 | PDE10A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842436-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING IMIDAZOPYRIMIDINE OR IMIDAZOTRIAZINE DERIVATIVES FOR USE IN THE TREATMENT OF SCHIZOPHRENIA | SK BIOPHARMACEUTICALS CO LTD (KR) | 2023-11-08 | — | — | EP | claimed |
| EP-0533837-A4 | INHIBITION OF 5-LIPOXYGENASE AND CYCLOOXYGENASE PATHWAY MEDIATED DISEASES | SMITHKLINE BEECHAM CORP (US) | 1994-11-17 | — | — | EP | claimed |
| EP-0533837-A1 | INHIBITION OF 5-LIPOXYGENASE AND CYCLOOXYGENASE PATHWAY MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-31 | — | — | EP | claimed |
| WO-1991019497-A1 | INHIBITION OF 5-LIPOXYGENASE AND CYCLOOXYGENASE PATHWAY MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-26 | — | — | WO | claimed |
| EP-0113236-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES-PYRAZINES, AND -TRIAZINES | ELI LILLY AND COMPANY (US) | 1987-04-22 | — | — | EP | claimed |
| EP-0185345-A1 | Imidazo derivatives, their preparation and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | claimed |
| EP-0113236-A1 | Substituted imidazopyrimidines-pyrazines, and -triazines | ELI LILLY AND COMPANY (US) | 1984-07-11 | — | — | EP | claimed |
| JP-11119369-A | — | — | None | — | — | JP | disclosed |
| EP-4665454-A1 | IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF | Dice Alpha, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250223291-A1 | IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS | INCYTE CORPORATION | 2025-07-10 | — | — | US | disclosed |
| WO-2025072384-A1 | 5/6-5/6-BISARYL COMPOUNDS AS TAK1 INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2025-04-03 | — | — | WO | disclosed |
| US-12084449-B2 | Imidazotriazines and imidazopyrimidines as kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2024-09-10 | — | — | US | disclosed |
| WO-2024173173-A1 | IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2024-08-22 | — | — | WO | disclosed |
| US-4994571-A | Reacting heterocycle-containing sulfonamide compound with carbonyl compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0404190-A1 | Condensed heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0305939-A1 | Process of producing sulfonylurea derivatives | Takeda Chemical Industries, Ltd. (JP) | 1989-03-08 | — | — | EP | disclosed |
| US-4716169-A | INOTROPIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1987-12-29 | — | — | US | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0185345-A1 | Imidazo derivatives, their preparation and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1986-06-25 | — | — | EP | disclosed |
| US-4503235-A | Process for producing 4-carbamoyl-1H-imidazolium-5-olate | WARNER-LAMBERT COMPANY (US) | 1985-03-05 | — | — | US | disclosed |