Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293161 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL24386614 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL19668950 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL20111501 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL20934789 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL8201762 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL28320315 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL25646955 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL23542539 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL23219895 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839798-A2 | Intermediates for preparating non-peptide retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5545750-A | TREATING HUMAN IMMUNODEFICIENCY VIRUS | ABBOTT LABORATORIES (US) | 1996-08-13 | — | — | US | disclosed |
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0402646-A1 | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |