Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | THPO | P40225 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.66 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.64 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.64 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350843 | 0.95 | MAPT (0.70) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10918103 | 0.95 | MAPT (0.70) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10742637 | 0.92 | MAPT (0.69) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9675181 | 0.92 | MEN1 (0.70) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7341750 | 0.92 | CACNA1F (0.70) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9672729 | 0.91 | CACNA1F (0.68) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7282141 | 0.90 | CACNA1F (0.69) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9674767 | 0.90 | CACNA1F (0.69) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7346945 | 0.90 | CACNA1F (0.69) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7274108 | 0.89 | CACNA1F (0.75) | MAPTMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591757-A | ADRENERGIC BETA-RECEPTOR BLOCKING AGENTS AND CALCIUM ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5110820-A | Hypotensive agents; cardiovascular disorders | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0151006-B1 | DIHYDROPYRIDINE COMPOUNDS, THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PRODUCING THESE COMPOSITIONS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0151006-A2 | Dihydropyridine compounds, their production, pharmaceutical compositions containing them, and methods of producing these compositions | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | disclosed |