Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083431 | 0.91 | SLC6A9 (0.45) | SLC6A9SLC6A5HPGDTSHRALDH1A1 | |
| SCHEMBL7286178 | 0.86 | MEN1 (0.46) | ALDH1A1MAPTSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11083435 | 0.86 | SLC6A9 (0.45) | SLC6A9SLC6A5HPGDTSHRALDH1A1 | |
| SCHEMBL7277305 | 0.84 | SLC6A9 (0.42) | SLC6A9SLC6A5HPGDTSHRALDH1A1 | |
| SCHEMBL7287247 | 0.84 | SLC6A9 (0.49) | SLC6A9SLC6A5HPGDTSHRALDH1A1 | |
| SCHEMBL7291148 | 0.83 | SMN1; SMN2 (0.46) | TSHRALDH1A1MAPTNPSR1 | |
| SCHEMBL11080632 | 0.83 | TSHR (0.44) | SLC6A9SLC6A5TSHR | |
| SCHEMBL11083984 | 0.82 | SLC6A9 (0.48) | SLC6A9SLC6A5HPGDTSHRALDH1A1 | |
| SCHEMBL7280219 | 0.82 | SLC6A9 (0.44) | SLC6A9SLC6A5HPGDTSHRALDH1A1 | |
| SCHEMBL11083150 | 0.81 | SLC6A9 (0.38) | SLC6A9SLC6A5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440941-A | Aroyl-aminoacids, amides and esters thereof | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0054936-A1 | Aroyl amino acids | USV PHARMACEUTICAL CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |