Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 10/20 | 0.51 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280327 | 1.00 | TP53 (0.52) | TP53TSHRPLA2G4BRARBPLK1 | |
| SCHEMBL7280292 | 0.92 | NR5A1 (0.56) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL7280293 | 0.92 | NR5A1 (0.56) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL7271288 | 0.83 | ALOX12 (0.44) | TP53TSHRPLA2G4BPLK1 | |
| SCHEMBL7271292 | 0.83 | ALOX12 (0.44) | TP53TSHRPLA2G4BPLK1 | |
| SCHEMBL7305891 | 0.82 | TP53 (0.48) | TP53TSHRPLA2G4BRARBPLK1 | |
| SCHEMBL7305899 | 0.82 | TP53 (0.48) | TP53TSHRPLA2G4BRARBPLK1 | |
| SCHEMBL7271369 | 0.80 | TP53 (0.64) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL7271374 | 0.80 | TP53 (0.64) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL11480233 | 0.79 | KMT2A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1638-H | CYCLIC HEXAPEPTIDE | FURUTA TAKAHISA (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0462531-B1 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0729974-A1 | Cyclic polypeptide with antibiotic activity and a process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5376634-A | Microbiocides | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0486011-A2 | Pharmaceutical composition against Pneumocystis carinii | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
| EP-0462531-A2 | Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |