Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7281902 | 0.99 | HTR3A (0.64) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL7268990 | 0.82 | HTR3A (0.69) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL31387673 | 0.82 | HTR3A (0.58) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| SCHEMBL7289440 | 0.82 | HTR3A (0.58) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL7276091 | 0.82 | HTR3A (0.68) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL7289083 | 0.81 | HTR3A (0.57) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Azasetron SCHEMBL19492326 | 0.79 | HTR3A (1.00) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Azasetron SCHEMBL17191 | 0.79 | HTR3A (1.00) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Azasetron SCHEMBL29880168 | 0.79 | HTR3A (1.00) | HTR3AKCNH2HTR2ASLC6A4HRH1 | |
| Azasetron SCHEMBL19463750 | 0.79 | HTR3A (1.00) | HTR3AKCNH2HTR2ASLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |