Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538161 | 0.90 | NAPRT (0.57) | NAPRTCYP1A2CYP3A4CYP2C9TDP1 | |
| SCHEMBL30917345 | 0.86 | NAPRT (0.65) | NAPRTCYP1A2CYP3A4CYP2C9TDP1 | |
| SCHEMBL8915193 | 0.86 | NAPRT (0.65) | NAPRTCYP1A2CYP3A4CYP2C9TDP1 | |
| SCHEMBL3253168 | 0.85 | NAPRT (0.74) | NAPRTCYP1A2CYP3A4CYP2C9TBXAS1 | |
| SCHEMBL21093385 | 0.85 | TDP1 (0.57) | NAPRTCYP1A2CYP3A4CYP2C9TDP1 | |
| SCHEMBL28975712 | 0.84 | NAPRT (0.62) | NAPRTCYP1A2CYP3A4CYP2C9TBXAS1 | |
| SCHEMBL30195679 | 0.84 | NAPRT (0.62) | NAPRTCYP1A2CYP3A4CYP2C9TBXAS1 | |
| SCHEMBL7430813 | 0.83 | NAPRT (0.61) | NAPRTCYP1A2CYP3A4CYP2C9TBXAS1 | |
| SCHEMBL16198319 | 0.82 | NAPRT (0.56) | NAPRTCYP1A2CYP3A4CYP2C9TBXAS1 | |
| SCHEMBL30120603 | 0.82 | NAPRT (0.56) | NAPRTCYP1A2CYP3A4CYP2C9TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291673-B1 | TETRAHYDROPYRIDINE OXIMES, A PROCESS FOR THEIR PREPARATION AND USE THEREOF AS CHOLINERGIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |
| US-5073561-A | N-substituted-pyridinyl oximes | WARNER-LAMBERT COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4929734-A | ANTIINFLAMMATORY AGENTS, ANTIDEPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4798841-A | COGNITION ACTIVATORS, ANALGESICS | WARNER-LAMBERT COMPANY (US) | 1989-01-17 | — | — | US | disclosed |
| EP-0291673-A1 | Tetrahydropyridine oximes, a process for their preparation and use thereof as cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-11-23 | — | — | EP | disclosed |
| US-4710508-A | ANALGESICS | WARNER-LAMBERT COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| US-4463008-A | 2-Alkoxy-5-(pyridinyl)pyridines and cardiotonic use thereof | STERLING DRUG INC. (US) | 1984-07-31 | — | — | US | disclosed |
| EP-0109027-A1 | Pyridine derivatives, process for their preparation and composition containing them | STERLING DRUG INC. (US) | 1984-05-23 | — | — | EP | disclosed |