Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28975712 | 1.00 | NAPRT (0.62) | NAPRTCYP3A4CYP1A2CYP2C9CHRNA7 | |
| SCHEMBL3253168 | 0.87 | NAPRT (0.74) | NAPRTCYP3A4CYP1A2CYP2C9RECQL | |
| SCHEMBL7430813 | 0.84 | NAPRT (0.61) | NAPRTCYP3A4CYP1A2CYP2C9RECQL | |
| SCHEMBL7280697 | 0.84 | NAPRT (0.61) | NAPRTCYP3A4CYP1A2CYP2C9RECQL | |
| SCHEMBL7362509 | 0.81 | NAPRT (0.72) | NAPRTCYP3A4CYP1A2CYP2C9RECQL | |
| SCHEMBL9433087 | 0.81 | NAPRT (0.57) | NAPRTCYP3A4CYP1A2CYP2C9RECQL | |
| SCHEMBL1538161 | 0.81 | NAPRT (0.57) | NAPRTCYP3A4CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL23932686 | 0.81 | CYP1A2 (0.63) | NAPRTCYP3A4CYP1A2CYP2C9CHRNA7 | |
| SCHEMBL16198319 | 0.80 | NAPRT (0.56) | NAPRTCYP3A4CYP1A2CYP2C9RECQL | |
| SCHEMBL10695581 | 0.80 | TBXAS1 (0.60) | NAPRTCYP3A4CYP1A2CYP2C9CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4144726-B1 | PREPARATION METHOD FOR SYNTHESIZING S-NICOTINE FROM GLUTARIC ACID ESTER | SHENZHEN ZINWI BIO TECH CO LTD (CN) | 2024-10-02 | — | — | EP | claimed |
| CN-113387925-B | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-113387925-B | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113387925-B | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2023284059-A1 | PREPARATION METHOD FOR SYNTHESIZING S-NICOTINE FROM GLUTARIC ACID ESTER | 深圳市真味生物科技有限公司 | 2023-01-19 | — | — | WO | disclosed |
| WO-2023284059-A1 | PREPARATION METHOD FOR SYNTHESIZING S-NICOTINE FROM GLUTARIC ACID ESTER | 深圳市真味生物科技有限公司 | 2023-01-19 | — | — | WO | disclosed |