Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282066 | 0.89 | ITGB3 (0.42) | ITGB3ITGA2BPRSS1PPARDPPARA | |
| Hydrochloric Acid SCHEMBL7281613 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BPRSS1PPARDPPARA | |
| SCHEMBL7273965 | 0.87 | ITGB3 (0.57) | ITGB3ITGA2BPRSS1TMPRSS15PPARD | |
| SCHEMBL7282152 | 0.87 | ITGB3 (0.57) | ITGB3ITGA2BPRSS1TMPRSS15PPARD | |
| SCHEMBL7283873 | 0.86 | F2 (0.41) | ITGB3ITGA2BPRSS1PPARDPPARA | |
| SCHEMBL7272698 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1TMPRSS15PPARD | |
| SCHEMBL7272941 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1TMPRSS15PPARD | |
| SCHEMBL7274111 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1TMPRSS15PPARD | |
| SCHEMBL7276120 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BPRSS1TMPRSS15PPARD | |
| Hydrochloric Acid SCHEMBL7387376 | 0.77 | F2 (0.46) | ITGB3ITGA2BPRSS1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | claimed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | claimed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |