Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.76 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.76 |
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273988 | 0.92 | ITGB3 (0.64) | ITGB3ITGA2BIRAK4LTA4H | |
| SCHEMBL7285046 | 0.90 | ITGB3 (0.73) | ITGB3ITGA2BPPARDPPARAFFAR1 | |
| SCHEMBL7273484 | 0.89 | ITGB3 (0.77) | ITGB3ITGA2BPPARDPPARAFFAR1 | |
| Fradafiban SCHEMBL380350 | 0.87 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Fradafiban SCHEMBL8863359 | 0.87 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Fradafiban SCHEMBL7280818 | 0.86 | ITGB3 (0.98) | ITGB3ITGA2B | |
| SCHEMBL7276254 | 0.85 | ITGB3 (0.72) | ITGB3ITGA2BPPARDPPARAFFAR1 | |
| SCHEMBL7273255 | 0.85 | ITGB3 (0.68) | ITGB3ITGA2BPPARDPPARAFFAR1 | |
| SCHEMBL7275650 | 0.83 | ITGB3 (0.63) | ITGB3ITGA2BIRAK4LTA4H | |
| Lefradafiban SCHEMBL7080546 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2BIRAK4LTA4HFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |