Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288722 | 1.00 | REN (0.43) | REN | |
| SCHEMBL7278739 | 0.85 | PSEN1 (0.37) | REN | |
| SCHEMBL7280239 | 0.79 | REN (0.39) | REN | |
| SCHEMBL7288831 | 0.79 | REN (0.39) | REN | |
| SCHEMBL7288374 | 0.78 | REN (0.48) | REN | |
| SCHEMBL7279096 | 0.74 | CCR1 (0.38) | REN | |
| SCHEMBL9388320 | 0.74 | REN (0.48) | REN | |
| SCHEMBL7278947 | 0.73 | REN (0.37) | REN | |
| SCHEMBL7287034 | 0.72 | REN (0.37) | REN | |
| SCHEMBL7280042 | 0.69 | REN (0.62) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589446-B1 | N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors | BOEHRINGER INGELHEIM CA LTD (CA) | 1997-09-03 | — | — | EP | claimed |
| WO-1994007845-A1 | N-(HYDROXYETHYL)BUTANEDIAMIDE DERIVATIVES AS RENIN INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-04-14 | — | — | WO | claimed |