SCHEMBL728121

SCHEMBL728121

CCCCNCCC[Si](OC)(OCC)OCC

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.38
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
MEN1 O00255 1/20 0.30
GLA P06280 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27841106 0.96 TSHR (0.39) TSHRALDH1A1LMNAADH1BADH1C
SCHEMBL729887 0.94 CYP2C19 (0.33) TSHRALDH1A1LMNAMEN1GLA
SCHEMBL24178934 0.92 LMNA (0.32) TSHRALDH1A1LMNAMEN1GLA
SCHEMBL15327667 0.90 CYP2C19 (0.33) TSHRALDH1A1LMNAMEN1GLA
SCHEMBL197661 0.90 TSHR (0.44) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL28710273 0.89 PAOX (0.37) TSHRALDH1A1LMNAHRH4HRH3
SCHEMBL29396656 0.88 TSHR (0.42) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL3623988 0.88 LMNA (0.36) TSHRALDH1A1LMNAMEN1GLA
SCHEMBL2257008 0.88 LMNA (0.36) TSHRALDH1A1LMNAMEN1GLA
SCHEMBL56471 0.88 LMNA (0.47) TSHRALDH1A1LMNAADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed