Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.52 |
| ▸ | FAAH | O00519 | 6/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23081203 | 0.78 | TRPV1 (0.47) | FAAHTRPV1 | |
| SCHEMBL25444628 | 0.78 | TRPV1 (0.47) | FAAHTRPV1 | |
| Hydrochloric Acid SCHEMBL29008440 | 0.74 | SMN1; SMN2 (0.68) | EPHX2FAAH | |
| SCHEMBL6099838 | 0.74 | NPSR1 (0.52) | CTSK | |
| SCHEMBL9839814 | 0.73 | EPHX2 (0.64) | EPHX2FAAHTRPV1CNR1CNR2 | |
| SCHEMBL9840800 | 0.73 | EPHX2 (0.64) | EPHX2FAAHTRPV1CNR1CNR2 | |
| SCHEMBL5862791 | 0.73 | SMN1; SMN2 (0.72) | EPHX2 | |
| SCHEMBL3809498 | 0.73 | EPHX2 (0.84) | EPHX2FAAHTRPV1CNR1CNR2 | |
| SCHEMBL2744272 | 0.71 | CETP (0.56) | FAAH | |
| SCHEMBL2745252 | 0.71 | CETP (0.56) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |