Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318152 | 0.89 | SLC9A1 (0.52) | SLC9A1HTR2CHTR2AHTR2BNPC1 | |
| SCHEMBL12020647 | 0.85 | SLC9A1 (0.49) | SLC9A1HTR2CHTR2AHTR2BNPC1 | |
| SCHEMBL12020648 | 0.85 | SLC9A1 (0.49) | SLC9A1HTR2CHTR2AHTR2BNPC1 | |
| SCHEMBL12020630 | 0.85 | SLC9A1 (0.49) | SLC9A1HTR2CHTR2AHTR2BNPC1 | |
| SCHEMBL726234 | 0.85 | SLC9A1 (0.49) | SLC9A1HTR2CHTR2AHTR2BNPC1 | |
| SCHEMBL12020631 | 0.85 | SLC9A1 (0.49) | SLC9A1HTR2CHTR2AHTR2BNPC1 | |
| SCHEMBL8357586 | 0.84 | SLC9A1 (0.67) | SLC9A1HTR2CHTR2AHTR2BKDM4E | |
| SCHEMBL14382757 | 0.81 | HTR2C (0.55) | SLC9A1HTR2CHTR2AHTR2BDDB1 | |
| SCHEMBL9007090 | 0.79 | HTR2C (0.51) | SLC9A1HTR2CHTR2AHTR2BDDB1 | |
| SCHEMBL15116689 | 0.78 | KCNQ3 (0.57) | SMN1; SMN2SLC6A2SLC6A4HPGDCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147576-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 1-AMINOMETHYL-2-PHENYL-CYCLOHEXANE COMPOUNDS | Grünenthal GmbH (DE) | 2011-12-01 | — | — | WO | disclosed |