Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785214 | 0.91 | MAOB (0.71) | MAOBL3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL712706 | 0.90 | CTSV (0.60) | MAOBL3MBTL1 | |
| SCHEMBL27934345 | 0.90 | MAOB (0.57) | MAOBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL10797158 | 0.89 | MAOB (0.72) | MAOBL3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL8888358 | 0.89 | LRRK2 (0.63) | MAOBL3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL711327 | 0.87 | MAOB (0.55) | MAOBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL29717104 | 0.87 | MAOB (0.55) | MAOBL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL15709261 | 0.87 | PARP15 (0.60) | MAOBL3MBTL1MAPT | |
| SCHEMBL6069637 | 0.86 | MAOB (0.64) | MAOBL3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL5528125 | 0.85 | MAOB (0.60) | MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391624-B1 | Substituted 1-[3-heteroarylmethoxy)phenyl] alkanols and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5248685-A | Substituted 1-[3-(heteroarylmethoxy)phenyl]alkanols and related compounds in the treatment of asthma | PFIZER INC. (US) | 1993-09-28 | — | — | US | disclosed |
| US-5061798-A | Intermediates in the formation of synthetic hormones, mimic effects of thyroid hormones; little or no effect on the heart | SMITH KLINE & FRENCH LABORATORIES, LTD. (GB) | 1991-10-29 | — | — | US | disclosed |
| EP-0188351-B1 | CHEMICAL COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-03-13 | — | — | EP | disclosed |
| CN-1010310-B | Preparation method of anti-hyperlipidemia agent | SMITH KLINE FRENCH LAB (GB) | 1990-11-07 | — | — | CN | disclosed |
| WO-1990012006-A1 | SUBSTITUTED 1-[3-(HETEROARYLMETHOXY)PHENYL]ALKANOLS AND RELATED COMPOUNDS IN THE TREATMENT OF ASTHMA, ARTHRITIS AND RELATED DISEASES | PFIZER INC. (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0391624-A1 | Substituted 1-[3-heteroarylmethoxy)phenyl] alkanols and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1990-10-10 | — | — | EP | disclosed |
| US-4910305-A | Containing a protected 4-hydroxyphenyl | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-03-20 | — | — | US | disclosed |
| US-4826876-A | WITHOUT EFFECT ON HEART | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-05-02 | — | — | US | disclosed |
| US-4766121-A | NOT AFFECTING THE HEART | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1988-08-23 | — | — | US | disclosed |
| CN-86100894-A | Process for the preparation of compounds | — | 1986-09-03 | — | — | CN | disclosed |
| EP-0188351-A2 | Chemical compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-07-23 | — | — | EP | disclosed |