Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292877 | 0.90 | REN (0.54) | RENP2RX1 | |
| SCHEMBL7282082 | 0.88 | REN (0.53) | RENP2RX1 | |
| SCHEMBL7293140 | 0.88 | REN (0.52) | RENP2RX1 | |
| SCHEMBL7303400 | 0.86 | REN (0.46) | REN | |
| SCHEMBL7306305 | 0.84 | REN (0.46) | REN | |
| SCHEMBL9800547 | 0.84 | REN (0.48) | REN | |
| SCHEMBL9227669 | 0.83 | REN (0.60) | REN | |
| SCHEMBL7283229 | 0.83 | REN (0.60) | REN | |
| SCHEMBL7282781 | 0.83 | REN (0.48) | REN | |
| SCHEMBL9800493 | 0.83 | REN (0.53) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332008-A2 | Peptide-like aminoacid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-09-13 | — | — | EP | disclosed |