Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283882 | 1.00 | SRC (0.50) | SRCERN1NPSR1ALDH1A1LMNA | |
| SCHEMBL7284734 | 0.82 | SRC (0.52) | SRCERN1NPSR1ALDH1A1LMNA | |
| SCHEMBL7283876 | 0.80 | SRC (0.50) | SRCERN1NPSR1ALDH1A1LMNA | |
| SCHEMBL6736649 | 0.78 | SRC (0.49) | SRCERN1NPSR1ALDH1A1LMNA | |
| SCHEMBL7290764 | 0.77 | SRC (0.47) | SRCERN1NPSR1ALDH1A1LMNA | |
| SCHEMBL28464657 | 0.77 | ERN1 (0.44) | SRCERN1NPSR1ALDH1A1LMNA | |
| SCHEMBL6737227 | 0.74 | ERN1 (0.57) | SRCERN1NPSR1ALDH1A1LMNA | |
| SCHEMBL4298275 | 0.74 | KMT2A (0.40) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL4298273 | 0.74 | KMT2A (0.40) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL9146840 | 0.73 | SRC (0.44) | SRCERN1NPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656362-B1 | Macrocyclic compounds and their use as pharmaceuticals | LILLY CO ELI (GB) | 1999-09-01 | — | — | EP | disclosed |
| US-5580900-A | TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1996-12-03 | — | — | US | disclosed |
| US-5574158-A | CRYPT COMPOUNDS, NERVOUS SYSTEM DISORDERS, CHELATE COMPOUNDS | LILLY INDUSTRIES LIMITED (GB) | 1996-11-12 | — | — | US | disclosed |
| EP-0656362-A1 | Novel compounds | LILLY INDUSTRIES LIMITED (GB) | 1995-06-07 | — | — | EP | disclosed |