Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161008 | 0.84 | POLB (0.39) | POLBALDH1A1GAAHPGDKMT2A | |
| SCHEMBL14424604 | 0.77 | POLB (0.36) | POLBALDH1A1GAAHPGDKMT2A | |
| SCHEMBL20271929 | 0.77 | SRC (0.47) | SRCPOLBALDH1A1GAAHPGD | |
| SCHEMBL7283891 | 0.77 | SRC (0.50) | ERN1SRCALDH1A1HPGDKMT2A | |
| SCHEMBL7283882 | 0.77 | SRC (0.50) | ERN1SRCALDH1A1HPGDKMT2A | |
| SCHEMBL23748226 | 0.77 | ALDH1A1 (0.46) | SRCPOLBALDH1A1GAAHPGD | |
| SCHEMBL6508732 | 0.77 | SRC (0.44) | ERN1SRCPOLBALDH1A1KMT2A | |
| SCHEMBL30593089 | 0.77 | ALDH1A1 (0.46) | SRCPOLBALDH1A1GAAHPGD | |
| SCHEMBL30251825 | 0.77 | SRC (0.47) | ERN1SRCPOLBALDH1A1GAA | |
| SCHEMBL25559298 | 0.76 | GAA (0.39) | POLBALDH1A1GAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107586285-B | Preparation method of 2, 3-dihydrobenzopyran-4-one derivative | 浙江圣效化学品有限公司 | 2020-09-01 | — | — | CN | disclosed |