SCHEMBL728393

SCHEMBL728393

C=CCNC(=O)C(O)=CO

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
LMNA P02545 2/20 0.38
FAAH O00519 1/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.35
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4687179 0.82 TSHR (0.45) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL4952777 0.80 TSHR (0.56) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL4933353 0.78
SCHEMBL3424075 0.77 ALDH1A1 (0.43) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL10914697 0.77 ALDH1A1 (0.43) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL29424 0.76
SCHEMBL9819713 0.74 TSHR (0.46) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL19063392 0.73 TSHR (0.45) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL2754316 0.73 TSHR (0.45) TSHRSMN1; SMN2MAPTKMT2AALDH1A1
SCHEMBL29988 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101857396-B Water-in-oil bitumen dispersions and prepare the method for paving compositions by it MEADWESTVACO CORP. (US) 2016-05-18 CN claimed
EP-2441804-B1 Water-in-oil bitumen dispersions and methods for producing paving compositions from the same MEADWESTVACO CORP (US) 2014-12-03 EP claimed
EP-2441804-A1 Water-in-oil bitumen dispersions and methods for producing paving compositions from the same MeadWestvaco Corporation (US) 2012-04-18 EP claimed
JP-4748818-B2 2011-08-17 JP claimed
CN-101857396-A Water-in-oil bitumen dispersions reaches and prepares the method for paving compositions by it MEADWESTVACO CORP (US) 2010-10-13 CN claimed
JP-2009531565-A 2009-09-03 JP claimed
EP-1915420-A4 WATER-IN-OIL BITUMEN DISPERSIONS AND METHODS FOR PRODUCING PAVING COMPOSITIONS FROM THE SAME MEADWESTVACO CORP (US) 2009-03-04 EP claimed
CN-101321814-A Water-in-oil bitumen dispersion and method for producing paving composition therefrom MEADWESTVACO CORP (US) 2008-12-10 CN claimed
EP-1915420-A2 WATER-IN-OIL BITUMEN DISPERSIONS AND METHODS FOR PRODUCING PAVING COMPOSITIONS FROM THE SAME MeadWestvaco Corporation (US) 2008-04-30 EP claimed
WO-2007112335-A2 WATER-IN-OIL BITUMEN DISPERSIONS AND METHODS FOR PRODUCING PAVING COMPOSITIONS FROM THE SAME MEADWESTVACO CORPORATION (US) 2007-10-04 WO claimed
EP-3394178-A1 ADHESIVE COMPOSITIONS WITH TUNABLE RHEOLOGICAL PROPERTIES Ingevity South Carolina, LLC (US) 2018-10-31 EP disclosed
WO-2017112915-A1 ADHESIVE COMPOSITIONS WITH TUNABLE RHEOLOGICAL PROPERTIES INGEVITY SOUTH CAROLINA, LLC (US) 2017-06-29 WO disclosed
CN-101857396-B Water-in-oil bitumen dispersions and prepare the method for paving compositions by it MEADWESTVACO CORP. (US) 2016-05-18 CN disclosed
EP-2441804-B1 Water-in-oil bitumen dispersions and methods for producing paving compositions from the same MEADWESTVACO CORP (US) 2014-12-03 EP disclosed
EP-2441804-A1 Water-in-oil bitumen dispersions and methods for producing paving compositions from the same MeadWestvaco Corporation (US) 2012-04-18 EP disclosed
CN-101679754-A Method for producing bitumen compositions MEADWESTVACO CORP (US) 2010-03-24 CN disclosed
CN-101321814-A Water-in-oil bitumen dispersion and method for producing paving composition therefrom MEADWESTVACO CORP (US) 2008-12-10 CN disclosed
US-4626571-A Dihydroxyacryl BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) 1986-12-02 US disclosed
US-4626581-A CROSSLINKED ACRYLAMIDE INTERPOLYMERS BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) 1986-12-02 US disclosed
US-4584402-A Dihydroxyacryl BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1986-04-22 US disclosed