Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840891 | 0.89 | ALDH1A1 (0.63) | PTGDR2HSD17B10LMNAALDH1A1MAPT | |
| SCHEMBL3292757 | 0.89 | ALDH1A1 (0.63) | PTGDR2PTPN7TSHRMCL1LMNA | |
| SCHEMBL29707984 | 0.89 | ALDH1A1 (0.63) | PTGDR2HSD17B10LMNAALDH1A1MAPT | |
| SCHEMBL29669441 | 0.89 | ALDH1A1 (0.63) | PTGDR2PTPN7TSHRMCL1LMNA | |
| SCHEMBL2558336 | 0.88 | PTGDR2 (0.54) | PTGDR2TSHRLMNAALDH1A1MAPT | |
| SCHEMBL7285781 | 0.87 | PTGDR2 (0.69) | PTGDR2PTPN7TSHRALOX15HSD17B10 | |
| SCHEMBL5302743 | 0.83 | PTGDR2 (0.63) | PTGDR2TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL7293656 | 0.83 | TRIM24 (0.57) | PTGDR2PTPN7TSHRALOX15HSD17B10 | |
| SCHEMBL23804143 | 0.82 | MCL1 (0.58) | PTGDR2PTPN7TSHRALOX15HSD17B10 | |
| SCHEMBL4241015 | 0.82 | PTGDR2 (0.61) | PTGDR2TSHRLMNAL3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |