Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 5/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273947 | 0.91 | EP300 (0.37) | ACLYEP300ABCB1HPGDABCG2 | |
| SCHEMBL7283703 | 0.91 | ABCB1 (0.35) | ACLYEP300ABCB1HPGDABCG2 | |
| Hydrochloric Acid SCHEMBL7284117 | 0.89 | F2 (0.39) | BRD4KMT2APDE4APDE4BPDE4C | |
| SCHEMBL7282659 | 0.88 | ABCB1 (0.36) | EP300ABCB1HPGDABCG2OPRM1 | |
| SCHEMBL7274966 | 0.88 | HRH3 (0.40) | EP300ABCB1HPGDABCG2OPRM1 | |
| SCHEMBL7280940 | 0.88 | ABCB1 (0.36) | EP300ABCB1HPGDABCG2BRD4 | |
| SCHEMBL7274992 | 0.88 | ABCB1 (0.35) | EP300ABCB1HPGDABCG2OPRM1 | |
| SCHEMBL7273419 | 0.86 | AR (0.39) | EP300ABCB1HPGDABCG2OPRM1 | |
| SCHEMBL7282551 | 0.86 | ABCB1 (0.44) | ABCB1HPGDABCG2OPRM1HTR1A | |
| SCHEMBL7281268 | 0.86 | ABCB1 (0.44) | ABCB1HPGDABCG2OPRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |