Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 20/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284401 | 1.00 | TBXAS1 (0.97) | TBXAS1 | |
| Hydrochloric Acid SCHEMBL1568842 | 0.99 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL2924561 | 0.99 | TBXAS1 (0.95) | TBXAS1 | |
| SCHEMBL2924566 | 0.99 | TBXAS1 (0.95) | TBXAS1 | |
| Hydrochloric Acid SCHEMBL727407 | 0.99 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL11062724 | 0.94 | TBXAS1 (0.86) | TBXAS1 | |
| SCHEMBL11062763 | 0.94 | TBXAS1 (0.86) | TBXAS1 | |
| SCHEMBL11067972 | 0.87 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL11067976 | 0.87 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL11067979 | 0.87 | TBXAS1 (1.00) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925869-A | REACTIVATING ENZYME ACETYLCHOLINESTERASE INHIBITED BY LETHAL DOSE OF SOMAN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-15 | — | — | US | claimed |
| US-4908380-A | Substituted 1,3-dioxane ether derivative; thromboxane A2 inhibitor | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-13 | — | — | US | claimed |
| EP-0300675-A2 | Method for the improvement of cyclosporine therapy | MERCK FROSST CANADA INC. (CA) | 1989-01-25 | — | — | EP | claimed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | claimed |
| JP-58216126-A | — | — | None | — | — | JP | disclosed |
| EP-0230035-B1 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID CO (US) | 1994-10-12 | — | — | EP | disclosed |
| EP-0300675-A2 | Method for the improvement of cyclosporine therapy | MERCK FROSST CANADA INC. (CA) | 1989-01-25 | — | — | EP | disclosed |
| US-4777257-A | CARDIOVASCULAR DISORDERS | DAIICHI SEIYAKU CO., LTD. (JP) | 1988-10-11 | — | — | US | disclosed |
| US-4731370-A | VASODILATOR, ANTICOAGULANT | TOYAMA CHEMICAL CO., LTD. (JP) | 1988-03-15 | — | — | US | disclosed |
| US-4728663-A | HYPOTENSIVE, ANTIARRHYTHMIA | AMERICAN CYANAMID COMPANY (US) | 1988-03-01 | — | — | US | disclosed |
| US-4713387-A | Vasodilating and platelet aggregation inhibiting 1,4 dihydropyridines with an imidazolyl or pyridyl containing ester | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |
| US-4665188-A | Certain [(1-imidazolyl)-lower-alkylene]-tetrahydronaphthalenecarboxylic acids or corresponding idan-carboxylic acids which are thromboxane A2 | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| JP-S58216126-A | AUXILIARY FOR DISSOLUTION | ONO PHARMACEUT CO LTD | 1983-12-15 | — | — | JP | disclosed |
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | disclosed |