Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10448479 | 1.00 | ANPEP (0.53) | ANPEPSIGMAR1TMPRSS11DPOLBMEN1 | |
| SCHEMBL27487680 | 1.00 | ANPEP (0.53) | ANPEPSIGMAR1TMPRSS11DPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL27488757 | 0.98 | ANPEP (0.52) | ANPEPSIGMAR1TMPRSS11DMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8617719 | 0.98 | ANPEP (0.52) | ANPEPSIGMAR1TMPRSS11DMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27530771 | 0.90 | ALDH1A1 (0.50) | ANPEPTMPRSS11DMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8617136 | 0.90 | ALDH1A1 (0.50) | ANPEPTMPRSS11DMEN1ALDH1A1KMT2A | |
| SCHEMBL5658130 | 0.89 | ANPEP (0.57) | ANPEPSIGMAR1POLBMEN1ALDH1A1 | |
| SCHEMBL8069933 | 0.89 | ANPEP (0.57) | ANPEPSIGMAR1POLBMEN1ALDH1A1 | |
| SCHEMBL5658127 | 0.89 | ANPEP (0.57) | ANPEPSIGMAR1POLBMEN1ALDH1A1 | |
| SCHEMBL18782332 | 0.89 | ANPEP (0.57) | ANPEPSIGMAR1POLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192746-A | Peptide derivatives and angiotensin IV receptor agonists | SAGAMI CHEM RES (JP) | 1998-09-09 | — | — | CN | disclosed |
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0357332-A2 | Renin inhibitors useful for the treatment of aids by inhibition of HIV protease | MERCK & CO. INC. (US) | 1990-03-07 | — | — | EP | disclosed |