Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4183355 | 0.84 | ERN1 (0.44) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL170690 | 0.80 | ERN1 (0.55) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL18570190 | 0.79 | ERN1 (0.35) | ERN1ALDH1A1NFE2L2 | |
| SCHEMBL953118 | 0.77 | ERN1 (0.48) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL27685686 | 0.77 | ERN1 (0.52) | ERN1TLR2TLR1TLR6CA1 | |
| Bromomethane SCHEMBL28079811 | 0.77 | ERN1 (0.52) | ERN1TLR2TLR1TLR6CA1 | |
| SCHEMBL1918798 | 0.76 | CA1 (0.57) | CA1CA2ACHEALDH1A1CA12 | |
| SCHEMBL25182547 | 0.74 | ERN1 (0.57) | ERN1CA1CA2ACHEALDH1A1 | |
| SCHEMBL9686221 | 0.73 | SMN1; SMN2 (0.45) | CA1CA2ACHEALDH1A1GAA | |
| SCHEMBL1028678 | 0.73 | ERN1 (0.63) | ERN1TLR2TLR1TLR6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |