SCHEMBL728479

SCHEMBL728479

COC(OC)(c1ccccc1)C(CCS)O[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 2/20 0.32
MEN1 O00255 1/20 0.32
TTR P02766 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MMP1 P03956 1/20 0.31
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730254 0.91 FOLH1 (0.33) MEN1TTRKMT2AALDH1A1GAA
SCHEMBL27579575 0.73 MAPK1 (0.33) MEN1TTRKMT2AALDH1A1GAA
SCHEMBL6909580 0.69 MAPK1 (0.33) MEN1KMT2AALDH1A1GAACES1
SCHEMBL151772 0.66 KCNN4 (0.37) MEN1KMT2AALDH1A1GAACES1
SCHEMBL10800116 0.65 CES1 (0.42) ALDH1A1CES1
SCHEMBL17183621 0.65 MAPK1 (0.39) MEN1KMT2AALDH1A1GAACES1
SCHEMBL705097 0.65 MAPK1 (0.36) MEN1TTRKMT2AALDH1A1
SCHEMBL10881161 0.64 MAPK1 (0.38) ALDH1A1CES1
SCHEMBL6554389 0.64 MAPK1 (0.38) ALDH1A1CES1
SCHEMBL708011 0.63 MAPK1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed