Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579052 | 0.88 | KMT2A (0.48) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL7273906 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL5493235 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL10994341 | 0.75 | CCR1 (0.44) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL12395373 | 0.75 | ALDH1A1 (0.56) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL7270443 | 0.75 | PTPRC (0.49) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL7700608 | 0.75 | TSHR (0.55) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL2353731 | 0.74 | ALDH1A1 (0.53) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL27573412 | 0.74 | KMT2A (0.60) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA | |
| SCHEMBL27573413 | 0.74 | KMT2A (0.60) | SMN1; SMN2HTTL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4795814-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTTS, ENZYME INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |