Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 3/20 | 0.34 |
| ▸ | MC3R | P41968 | 3/20 | 0.34 |
| ▸ | MC5R | P33032 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272371 | 0.93 | FFAR1 (0.41) | FFAR1S1PR1SSTR5 | |
| SCHEMBL7284926 | 0.89 | FFAR1 (0.41) | FFAR1S1PR1SSTR5 | |
| SCHEMBL7274755 | 0.89 | FFAR1 (0.41) | FFAR1S1PR1SSTR5 | |
| SCHEMBL7284295 | 0.88 | S1PR1 (0.40) | FFAR1S1PR1SSTR5 | |
| Hydrochloric Acid SCHEMBL7274706 | 0.88 | FFAR1 (0.40) | FFAR1S1PR1SSTR5 | |
| SCHEMBL7273858 | 0.87 | FFAR1 (0.42) | FFAR1MC4RMC3RMC5R | |
| SCHEMBL7274052 | 0.87 | FFAR1 (0.43) | FFAR1S1PR1 | |
| SCHEMBL7280816 | 0.86 | SSTR5 (0.43) | FFAR1SSTR5 | |
| Water SCHEMBL7277736 | 0.86 | SIGMAR1 (0.41) | FFAR1S1PR1SSTR5 | |
| SCHEMBL7276162 | 0.86 | FFAR1 (0.41) | FFAR1S1PR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |