SCHEMBL7285233

SCHEMBL7285233

CCCCC(=O)Oc1ccc(C=O)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.81
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 3/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
HSD17B10 Q99714 1/20 0.49
EGFR P00533 3/20 0.48
ERBB2 P04626 3/20 0.48
MIF P14174 1/20 0.47
BCL9 O00512 1/20 0.46
CTNNB1 P35222 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
RECQL P46063 1/20 0.45
HPGD P15428 1/20 0.45
RET P07949 1/20 0.45
CYP2A6 P11509 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3172173 0.95 KMT2A (0.84) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL13263852 0.94 KMT2A (0.81) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL9746611 0.94 KMT2A (0.81) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL1665845 0.94 KMT2A (0.81) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL28437309 0.94 KMT2A (0.81) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL1665645 0.90 KMT2A (0.74) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL14575315 0.90 KMT2A (0.93) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL14575820 0.90 KMT2A (1.00) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL5822065 0.88 KMT2A (0.61) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL5386778 0.87 KMT2A (0.70) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250135059-A1 COMPOSITIONS COMPRISING FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY 2025-05-01 US disclosed
CN-108047105-B 3-/4-ester-group-substituted benzaldehyde thiosemicarbazone derivative and preparation and application thereof 广东轻工职业技术学院 2020-06-26 CN disclosed
US-4760064-A Cardiotonic agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-07-26 US disclosed
EP-0187322-A1 Carbostyril compounds, compositions containing same and processes for preparing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-07-16 EP disclosed
US-4156696-A Fluoroaliphaticsulfonyl substituted methanes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-05-29 US disclosed
US-4069233-A Fluoroaliphaticsulfonyl substituted ethylenes substituted by furyl, thenyl, or 1H-pyrrolyl groups MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-01-17 US disclosed
US-3984357-A Fluoroaliphaticsulfonyl substituted ethylenes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-10-05 US disclosed
US-3932526-A Fluoroaliphaticsulfonyl substituted ethylenes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-01-13 US disclosed