SCHEMBL1665845

SCHEMBL1665845

CCCCCCCC(=O)Oc1ccc(C=O)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.81
SMN1; SMN2 Q16637 1/20 0.57
RET P07949 1/20 0.51
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
TOP2A P11388 2/20 0.48
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.46
EGFR P00533 1/20 0.46
ERBB2 P04626 1/20 0.46
POLM Q9NP87 1/20 0.46
POLK Q9UBT6 1/20 0.46
POLL Q9UGP5 1/20 0.46
POLH Q9Y253 1/20 0.46
ESR1 P03372 1/20 0.45
HPGD P15428 1/20 0.45
CA2 P00918 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9746611 1.00 KMT2A (0.81) KMT2ASMN1; SMN2RETNPC1RAB9A
SCHEMBL13263852 1.00 KMT2A (0.81) KMT2ASMN1; SMN2RETNPC1RAB9A
SCHEMBL28437309 1.00 KMT2A (0.81) KMT2ASMN1; SMN2RETNPC1RAB9A
SCHEMBL3172173 0.98 KMT2A (0.84) KMT2ASMN1; SMN2RETNPC1RAB9A
SCHEMBL7285233 0.94 KMT2A (0.81) KMT2ASMN1; SMN2RETALDH1A1LMNA
SCHEMBL5386778 0.93 KMT2A (0.70) KMT2ASMN1; SMN2RETALDH1A1LMNA
SCHEMBL14575820 0.90 KMT2A (1.00) KMT2ASMN1; SMN2ALDH1A1LMNAMAPT
SCHEMBL15430731 0.89 KMT2A (0.65) KMT2ASMN1; SMN2RETNPC1RAB9A
SCHEMBL5696854 0.88 KMT2A (0.68) KMT2ASMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL38661498 0.88 KMT2A (0.68) KMT2ASMN1; SMN2NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116556083-B Polyester cotton short-process dyeing process 浙江红绿蓝纺织印染有限公司 2024-02-27 CN claimed
CN-116556083-A Polyester cotton short-process dyeing process 浙江红绿蓝纺织印染有限公司 2023-08-08 CN claimed
CN-116556083-B Polyester cotton short-process dyeing process 浙江红绿蓝纺织印染有限公司 2024-02-27 CN disclosed
CN-116556083-A Polyester cotton short-process dyeing process 浙江红绿蓝纺织印染有限公司 2023-08-08 CN disclosed
CN-108047105-B 3-/4-ester-group-substituted benzaldehyde thiosemicarbazone derivative and preparation and application thereof 广东轻工职业技术学院 2020-06-26 CN disclosed
CN-108047105-A 3-/4- ester group substituted benzaldehyde thiosemicarbazone derivatives and its preparation and application 广东轻工职业技术学院 2018-05-18 CN disclosed
EP-2493905-B1 BISPHOSPHONATE COMPOUNDS FOR TREATING BONE METABOLISM DISORDERS WARNER CHILCOTT CO LLC (PR) 2016-11-30 EP disclosed
EP-2493905-B1 BISPHOSPHONATE COMPOUNDS FOR TREATING BONE METABOLISM DISORDERS WARNER CHILCOTT CO LLC (PR) 2016-11-30 EP disclosed
US-8822435-B2 Bisphosphonate compounds WARNER CHILCOTT COMPANY, LLC (US) 2014-09-02 US disclosed
US-8822435-B2 Bisphosphonate compounds WARNER CHILCOTT COMPANY, LLC (US) 2014-09-02 US disclosed
US-8822435-B2 Bisphosphonate compounds WARNER CHILCOTT COMPANY, LLC (US) 2014-09-02 US disclosed
US-20110098251-A1 BISPHOSPHONATE COMPOUNDS WARNER CHILCOTT COMPANY, LLC (US) 2011-04-28 US disclosed
US-20110098251-A1 BISPHOSPHONATE COMPOUNDS WARNER CHILCOTT COMPANY, LLC (US) 2011-04-28 US disclosed
US-20110098251-A1 BISPHOSPHONATE COMPOUNDS WARNER CHILCOTT COMPANY, LLC (US) 2011-04-28 US disclosed
EP-0152217-B1 LIQUID CRYSTALLINE CARBONIC ACID ESTERS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM Chisso Corporation (JP) 1990-08-29 EP disclosed
EP-0153826-B1 LIQUID-CRYSTALLINE SUBSTITUTED BIPHENYL ESTERS Chisso Corporation (JP) 1990-06-13 EP disclosed
US-4737313-A OPITICALLY ACTIVE CHISSO CORPORATION (JP) 1988-04-12 US disclosed
US-4647398-A Liquid-crystalline carbonic acid esters and liquid crystal compositions containing same CHISSO CORPORATION (JP) 1987-03-03 US disclosed
EP-0153826-A2 Liquid-crystalline substituted biphenyl esters Chisso Corporation (JP) 1985-09-04 EP disclosed
EP-0152217-A2 Liquid crystalline carbonic acid esters and liquid crystal compositions containing them Chisso Corporation (JP) 1985-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098251-A1 BISPHOSPHONATE COMPOUNDS BPGM, PPIP5K2, PTEN KMT2A 4240/4885SMN1; SMN2 2670/4885RET 3776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.