Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 19/20 | 0.73 |
| ▸ | CTRC | Q99895 | 5/20 | 0.73 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282754 | 0.85 | ELANE (0.75) | ELANECTRC | |
| SCHEMBL7273863 | 0.84 | ELANE (1.00) | ELANECTRC | |
| SCHEMBL2801889 | 0.82 | ELANE (0.65) | ELANECTRCCASP1 | |
| SCHEMBL7447790 | 0.77 | ELANE (0.69) | ELANECTRC | |
| SCHEMBL7274723 | 0.76 | ELANE (0.73) | ELANECTRC | |
| SCHEMBL7442027 | 0.74 | ELANE (0.64) | ELANECTRC | |
| SCHEMBL30280076 | 0.74 | CTRB1 (0.52) | ELANE | |
| SCHEMBL8641725 | 0.74 | ELANE (0.56) | ELANECTRCCASP1 | |
| SCHEMBL7441333 | 0.74 | ELANE (0.71) | ELANECTRC | |
| SCHEMBL7274215 | 0.73 | ELANE (0.74) | ELANECTRCCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |