SCHEMBL7285302

SCHEMBL7285302

COc1cc(C=O)c(O)c(C=O)c1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 18/20 0.62
TRIM24 O15164 1/20 0.57
TYR P14679 1/20 0.57
TRIM33 Q9UPN9 1/20 0.57
ALDH1A1 P00352 1/20 0.48
TLR2 O60603 1/20 0.47
TLR1 Q15399 1/20 0.47
TLR6 Q9Y2C9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3645435 0.90 ERN1 (0.61) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL28292328 0.90 ERN1 (0.61) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL28282933 0.90 ERN1 (0.56) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL13855640 0.88 ERN1 (0.55) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL931983 0.88 ERN1 (0.60) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL118908 0.88 ERN1 (0.68) ERN1ALDH1A1
SCHEMBL4376307 0.86 ERN1 (0.58) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL13980464 0.86 ERN1 (0.53) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL3928147 0.86 ERN1 (0.58) ERN1TRIM24TYRTRIM33ALDH1A1
SCHEMBL23796830 0.83 ERN1 (0.50) ERN1TRIM24TYRTRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241996-A PBT composite material and preparation method thereof 东风汽车集团股份有限公司 2025-01-03 CN claimed
CN-113801100-B Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-05-06 CN claimed
CN-113845535-B Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-03-08 CN claimed
CN-113845535-A Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2021-12-28 CN claimed
CN-113801100-A Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2021-12-17 CN claimed
CN-119661461-A Sulfur-containing macrocyclic binuclear nickel complex and preparation method and application thereof 广西师范大学 2025-03-21 CN disclosed
CN-119241996-A PBT composite material and preparation method thereof 东风汽车集团股份有限公司 2025-01-03 CN disclosed
CN-114395233-B Degradable plastic and preparation method thereof 清华大学 2022-10-25 CN disclosed
CN-113801100-B Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-05-06 CN disclosed
CN-114395233-A Degradable plastic and preparation method thereof 清华大学 2022-04-26 CN disclosed
CN-113845535-B Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2022-03-08 CN disclosed
CN-113845535-A Binuclear cadmium complex and preparation method and application thereof 四川省产品质量监督检验检测院 2021-12-28 CN disclosed
CN-113801100-A Tetranuclear copper complex and preparation method and application thereof 四川省产品质量监督检验检测院 2021-12-17 CN disclosed
EP-0656362-B1 Macrocyclic compounds and their use as pharmaceuticals LILLY CO ELI (GB) 1999-09-01 EP disclosed
US-5580900-A TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEM LILLY INDUSTRIES LIMITED (GB) 1996-12-03 US disclosed
US-5574158-A CRYPT COMPOUNDS, NERVOUS SYSTEM DISORDERS, CHELATE COMPOUNDS LILLY INDUSTRIES LIMITED (GB) 1996-11-12 US disclosed
EP-0656362-A1 Novel compounds LILLY INDUSTRIES LIMITED (GB) 1995-06-07 EP disclosed