Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 15/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285302 | 0.88 | ERN1 (0.62) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL28292328 | 0.82 | ERN1 (0.61) | ERN1TRIM24TYRTRIM33CYP3A4 | |
| SCHEMBL28282933 | 0.82 | ERN1 (0.56) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL3645435 | 0.82 | ERN1 (0.61) | ERN1TRIM24TYRTRIM33CYP3A4 | |
| SCHEMBL118908 | 0.81 | ERN1 (0.68) | ERN1ALDH1A1 | |
| SCHEMBL931983 | 0.81 | ERN1 (0.60) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL14877339 | 0.80 | ERN1 (0.48) | ERN1TRIM24TYRTRIM33CYP3A4 | |
| SCHEMBL11064540 | 0.80 | ERN1 (0.48) | ERN1TRIM24TYRTRIM33CYP3A4 | |
| SCHEMBL3928147 | 0.79 | ERN1 (0.58) | ERN1TRIM24TYRTRIM33ALDH1A1 | |
| SCHEMBL4376307 | 0.79 | ERN1 (0.58) | ERN1TRIM24TYRTRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282712-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI THERAPEUTICS INC (US) | 2025-09-11 | — | — | US | disclosed |
| US-20250282708-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI THERAPEUTICS, INC. (US) | 2025-09-11 | — | — | US | disclosed |
| US-12351537-B2 | Dimethoxyphenylalkylamine activators of serotonin receptors | ATAI THERAPEUTICS, INC. (US) | 2025-07-08 | — | — | US | disclosed |
| US-12344570-B2 | Aminotetraline activators of serotonin receptors | ATAI THERAPEUTICS, INC. (US) | 2025-07-01 | — | — | US | disclosed |
| EP-4457203-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Therapeutics, Inc. (US) | 2024-11-06 | — | — | EP | disclosed |
| US-20240300885-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Life Sciences AG (DE) | 2024-09-12 | — | — | US | disclosed |
| US-20240294461-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. | 2024-09-05 | — | — | US | disclosed |
| EP-4351548-A2 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| US-11926574-B2 | Dimethoxyphenylalkylamine activators of serotonin receptors | Atai Therapeutics Inc. (US) | 2024-03-12 | — | — | US | disclosed |
| CN-117500487-A | Dimethoxy phenyl alkylamine activators of serotonin receptors | 恩泰奥吉尼克斯生物科学公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | Atai Therapeutics Inc. | 2023-05-04 | — | — | US | disclosed |
| WO-2022261240-A2 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Life Sciences AG (DE) | 2022-12-15 | — | — | WO | disclosed |
| WO-2022261240-A2 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | ATAI Life Sciences AG (DE) | 2022-12-15 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20160097755-A1 | METHOD FOR DETECTING, CAPTURING AND/OR RELEASING CHEMICAL ELEMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-04-07 | — | — | US | disclosed |
| US-8895559-B2 | Quinoxalines derivatives and pharmaceutical compositions and kits | MERCK PATENT GMBH (DE) | 2014-11-25 | — | — | US | disclosed |
| US-20130217670-A1 | QUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | US | disclosed |
| US-20090124787-A1 | Method for Producing Polyhydroxyalkanoates | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-14 | — | — | US | disclosed |
| US-20090124787-A1 | Method for Producing Polyhydroxyalkanoates | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-14 | — | — | US | disclosed |
| EP-1874845-B1 | METHOD FOR PRODUCING POLYHYDROXYALKANOATES | BASF SE (DE) | 2008-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300885-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR3B, HTR1B, TAAR5 | ERN1 4355/4885TRIM24 3675/4885TYR 799/4885 |
| US-20130217670-A1 | QUINOXALINE DERIVATIVES | PIK3R5, NQO2, PIK3R1 | ERN1 1611/4885TRIM24 2752/4885TYR 1567/4885 |
| US-11926574-B2 | Dimethoxyphenylalkylamine activators of serotonin receptors | HTR1A, HTR7, HTR4 | ERN1 2362/4885TRIM24 2757/4885TYR 234/4885 |
| US-20230138118-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR1A, HTR7, HTR4 | ERN1 2362/4885TRIM24 2757/4885TYR 234/4885 |
| US-12351537-B2 | Dimethoxyphenylalkylamine activators of serotonin receptors | HTR1A, HTR7, HTR4 | ERN1 2362/4885TRIM24 2757/4885TYR 234/4885 |
| US-20250282708-A1 | AMINOTETRALINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR3B, HTR1B, TAAR5 | ERN1 4355/4885TRIM24 3675/4885TYR 799/4885 |
| US-12344570-B2 | Aminotetraline activators of serotonin receptors | HTR3B, HTR1B, TAAR5 | ERN1 4355/4885TRIM24 3675/4885TYR 799/4885 |
| US-20090124787-A1 | Method for Producing Polyhydroxyalkanoates | LDHB, ACADM, HSD17B12 | ERN1 1195/4885TRIM24 2198/4885TYR 3092/4885 |
| US-20250282712-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR1A, HTR7, HTR4 | ERN1 2362/4885TRIM24 2757/4885TYR 234/4885 |
| US-20240294461-A1 | DIMETHOXYPHENYLALKYLAMINE ACTIVATORS OF SEROTONIN RECEPTORS | HTR1A, HTR7, HTR4 | ERN1 2362/4885TRIM24 2757/4885TYR 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.