Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.35 |
| ▸ | HRH2 | P25021 | 6/20 | 0.35 |
| ▸ | HRH1 | P35367 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283159 | 0.94 | ABCB1 (0.42) | ABCB1HPGDABCG2L3MBTL1MAOB | |
| SCHEMBL7282764 | 0.94 | ABCB1 (0.42) | ABCB1HPGDABCG2L3MBTL1MAOB | |
| SCHEMBL7274156 | 0.94 | ABCB1 (0.42) | ABCB1HPGDABCG2L3MBTL1MAOB | |
| SCHEMBL7282205 | 0.94 | ABCB1 (0.41) | ABCB1HPGDABCG2L3MBTL1MAOB | |
| SCHEMBL7275999 | 0.90 | CYP19A1 (0.40) | ABCB1HPGDABCG2MAOBMEN1 | |
| SCHEMBL7273794 | 0.89 | MAOB (0.39) | ABCB1HPGDABCG2MAOBMEN1 | |
| SCHEMBL7285068 | 0.88 | HRH3 (0.41) | MEN1KMT2AHRH3HRH2HRH1 | |
| SCHEMBL7272780 | 0.86 | MEN1 (0.39) | MEN1KMT2AHRH3HRH2HRH1 | |
| SCHEMBL7273518 | 0.86 | ABCB1 (0.46) | ABCB1HPGDABCG2L3MBTL1MAOB | |
| SCHEMBL7281199 | 0.85 | SLC6A2 (0.37) | ABCB1HPGDABCG2MAOBHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |