Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674027 | 0.87 | CYP4F2 (0.49) | ACHEALOX5PPARGPPARA | |
| SCHEMBL27654139 | 0.85 | ACHE (0.64) | ACHEALOX5PPARGPPARA | |
| SCHEMBL23996159 | 0.85 | KMT2A (0.57) | ACHEALOX5PPARGPPARABCL9 | |
| SCHEMBL7415777 | 0.83 | TSHR (0.46) | ACHEBCL9CTNNB1 | |
| SCHEMBL7282839 | 0.82 | PPARA (0.54) | PPARGPPARA | |
| SCHEMBL421378 | 0.82 | BCL9 (0.53) | ACHEBCL9CTNNB1 | |
| SCHEMBL27775300 | 0.82 | ACHE (0.49) | ACHEBCL9CTNNB1 | |
| SCHEMBL1125418 | 0.82 | ACHE (0.44) | ACHEBCL9CTNNB1 | |
| SCHEMBL10411693 | 0.81 | BCL9 (0.54) | BCL9CTNNB1 | |
| SCHEMBL27654134 | 0.80 | ACHE (0.43) | ACHEALOX5PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691341-A | ANTILEUKEMIA AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5464833-A | Anticarcinogenic agents, antiretrovirus agents or autoimmune diseases | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0623598-A1 | APOPTOSIS REGULATOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |