Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.43 |
| ▸ | F2R | P25116 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101067 | 0.98 | ABL1 (0.44) | ABL1EPHX1F2RHDAC11HDAC8 | |
| SCHEMBL7279003 | 0.94 | F2R (0.47) | ABL1EPHX1F2RHTTALDH1A1 | |
| SCHEMBL5540239 | 0.87 | MAPT (0.44) | F2RHTTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3476587 | 0.84 | ABL1 (0.47) | ABL1ALDH1A1KCNH3MAPTCNR1 | |
| SCHEMBL28133362 | 0.83 | ABL1 (0.44) | ABL1ALDH1A1KCNH3MAPT | |
| SCHEMBL3662823 | 0.81 | ABL1 (0.54) | ABL1EPHX1F2RHDAC11HDAC8 | |
| SCHEMBL11562950 | 0.80 | ABL1 (0.47) | ABL1EPHX1HTTALDH1A1KCNH3 | |
| SCHEMBL11558998 | 0.80 | ABL1 (0.47) | ABL1EPHX1HTTALDH1A1KCNH3 | |
| SCHEMBL11561223 | 0.80 | ABL1 (0.47) | ABL1EPHX1HTTALDH1A1KCNH3 | |
| SCHEMBL11074894 | 0.80 | ABL1 (0.47) | ABL1EPHX1HTTALDH1A1KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691341-A | ANTILEUKEMIA AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5464833-A | Anticarcinogenic agents, antiretrovirus agents or autoimmune diseases | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0623598-A1 | APOPTOSIS REGULATOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |