SCHEMBL3662823

SCHEMBL3662823

CCCCCNc1cccc(NCCCCC)c1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.54
MAPT P10636 2/20 0.52
HTT P42858 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C19 P33261 2/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
KCNH3 Q9ULD8 2/20 0.51
F2R P25116 2/20 0.51
ALDH1A1 P00352 3/20 0.48
EPHX1 P07099 6/20 0.45
ADRA2A P08913 1/20 0.44
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8667014 0.93 F2R (0.56) ABL1MAPTHTTCYP1A2CYP2D6
SCHEMBL22176875 0.92 ABL1 (0.53) ABL1MAPTHTTCYP1A2CYP2D6
SCHEMBL13383271 0.91 ABL1 (0.47) ABL1MAPTHTTCYP1A2CYP2D6
SCHEMBL10439139 0.89 ABL1 (0.54) ABL1MAPTHTTCYP1A2CYP2D6
SCHEMBL20197373 0.88 MAPT (0.71) ABL1MAPTHTTCYP1A2CYP2D6
SCHEMBL2920696 0.88 EPHX1 (0.59) ABL1MAPTALDH1A1EPHX1
SCHEMBL6231348 0.88 ABL1 (0.49) ABL1MAPTHTTCYP1A2CYP2D6
SCHEMBL5609022 0.87 MAPT (0.69) ABL1MAPTHTTCYP1A2CYP2D6
SCHEMBL19968723 0.87 ABL1 (0.51) ABL1MAPTHTTCYP1A2CYP2D6
SCHEMBL4611763 0.87 ABL1 (0.47) ABL1MAPTHTTCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2142496-B1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RES & ENG CO (US) 2013-04-17 EP disclosed
US-8080601-B2 Lubricating compositions containing ashless catalytic antioxidant additives EXXOMMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-12-20 US disclosed
EP-2142496-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2010-01-13 EP disclosed
US-20080248984-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2008-10-09 US disclosed
WO-2008121304-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-10-09 WO disclosed
US-5710335-A REACTING RESORCIN WITH PRIMARY AMINE THEN ALKYL HALIDE MITSUI TOATSU CHEMICALS, INC. (JP) 1998-01-20 US disclosed
EP-0111844-B1 PROCESS FOR THE PREPARATION OF 3-ACYLAMINOANILINES HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-27 EP disclosed
US-4552699-A Process for the preparation of 3-acylaminoanilines HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-12 US disclosed
EP-0111844-A1 Process for the preparation of 3-acylaminoanilines HOECHST AKTIENGESELLSCHAFT (DE) 1984-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080248984-A1 Lubricating compositions containing ashless catalytic antioxidant additives GPX1, SOD1, CAT ABL1 1077/4885MAPT 1203/4885HTT 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.