Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRHR | P34981 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285438 | 1.00 | XIAP (0.46) | XIAPPOLBKMT2AL3MBTL1TRHR | |
| SCHEMBL7273990 | 0.89 | ELANE (0.43) | XIAPKMT2ATRHR | |
| SCHEMBL7282397 | 0.89 | CAPN1 (0.41) | TRHR | |
| SCHEMBL7282406 | 0.89 | CAPN1 (0.41) | TRHR | |
| SCHEMBL7276794 | 0.83 | XIAP (0.46) | XIAPPOLBKMT2AL3MBTL1TRHR | |
| SCHEMBL7276782 | 0.83 | XIAP (0.46) | XIAPPOLBKMT2AL3MBTL1TRHR | |
| SCHEMBL7273766 | 0.82 | TRHR (0.47) | TRHR | |
| SCHEMBL7271564 | 0.82 | TRHR (0.47) | KMT2ATRHR | |
| SCHEMBL7280675 | 0.81 | KMT2A (0.45) | XIAPPOLBKMT2AL3MBTL1TRHR | |
| SCHEMBL7280679 | 0.81 | KMT2A (0.45) | XIAPPOLBKMT2AL3MBTL1TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473993-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |