Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.62 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283786 | 0.89 | ITGB3 (0.73) | ITGB3ITGA2BPPARDPPARAIRAK4 | |
| SCHEMBL7277434 | 0.85 | ITGB3 (0.80) | ITGB3ITGA2BPPARDPPARASMN1; SMN2 | |
| SCHEMBL7273790 | 0.83 | ITGB3 (0.70) | ITGB3ITGA2BPPARDPPARAIRAK4 | |
| SCHEMBL7280863 | 0.82 | ITGB3 (0.61) | ITGB3ITGA2BPPARDPPARAIRAK4 | |
| SCHEMBL7283795 | 0.81 | ITGB3 (0.71) | ITGB3ITGA2BPPARDPPARAIRAK4 | |
| SCHEMBL7284188 | 0.81 | ITGB3 (0.71) | ITGB3ITGA2BPPARDPPARAIRAK4 | |
| SCHEMBL7284309 | 0.79 | ITGB3 (0.71) | ITGB3ITGA2BPPARDPPARAIRAK4 | |
| SCHEMBL7277088 | 0.77 | ITGB3 (0.78) | ITGB3ITGA2BPPARDPPARAIRAK4 | |
| SCHEMBL7275425 | 0.77 | ITGB3 (0.81) | ITGB3ITGA2BPPARDPPARAIRAK4 | |
| SCHEMBL7275588 | 0.77 | ITGB3 (0.81) | ITGB3ITGA2BPPARDPPARAIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |