Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281577 | 0.81 | SIGMAR1 (0.43) | SIGMAR1MEN1KMT2AGAAGRM2 | |
| SCHEMBL7281681 | 0.81 | SIGMAR1 (0.40) | OPRM1SIGMAR1GAAGRM2 | |
| SCHEMBL7275891 | 0.77 | MEN1 (0.46) | SIGMAR1MEN1KMT2ASLC6A1SLC6A11 | |
| SCHEMBL8882623 | 0.77 | GRIN1 (0.42) | SIGMAR1SMN1; SMN2GRM2 | |
| SCHEMBL7284991 | 0.74 | MEN1 (0.48) | SIGMAR1MEN1KMT2ASLC6A1SLC6A11 | |
| SCHEMBL7273547 | 0.73 | SMN1; SMN2 (0.47) | SIGMAR1MEN1KMT2ASLC6A1SLC6A11 | |
| SCHEMBL7282097 | 0.70 | MEN1 (0.40) | SIGMAR1MEN1KMT2ASLC6A1SLC6A11 | |
| SCHEMBL7274018 | 0.67 | HCRTR2 (0.48) | SIGMAR1MEN1KMT2A | |
| SCHEMBL21133810 | 0.65 | GAA (0.47) | OPRM1SIGMAR1MEN1KMT2AGAA | |
| SCHEMBL3907755 | 0.65 | SIGMAR1 (0.44) | SIGMAR1MEN1KMT2ASLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |