Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 3/20 | 0.34 |
| ▸ | HMGCR | P04035 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287951 | 0.79 | HMGCR (0.47) | PTPN7HMGCRKMT2ARECQLTDP1 | |
| SCHEMBL9799605 | 0.78 | RAB9A (0.37) | PTPN7HMGCRRAB9ARECQLTDP1 | |
| SCHEMBL31336402 | 0.76 | RAB9A (0.48) | PTPN7HMGCRRAB9AKMT2ARECQL | |
| SCHEMBL9208114 | 0.76 | RAB9A (0.36) | PTPN7HMGCRRAB9ARECQLTDP1 | |
| SCHEMBL29421491 | 0.75 | HMGCR (0.39) | PTPN7HMGCRRAB9ARECQLTDP1 | |
| SCHEMBL7279050 | 0.74 | MAPT (0.40) | KMT2A | |
| SCHEMBL8078444 | 0.74 | KMT2A (0.50) | KMT2A | |
| SCHEMBL3621240 | 0.74 | RAB9A (0.43) | PTPN7HMGCRRAB9AKMT2ARECQL | |
| SCHEMBL2121380 | 0.73 | RAB9A (0.32) | PTPN7HMGCRRAB9A | |
| SCHEMBL7638150 | 0.72 | HMGCR (0.39) | PTPN7HMGCRRAB9AKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782160-A | CALCIUM RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0276552-A1 | 1,4-dihydropyridine derivatives and their production | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |