Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7285702 | 0.99 | GLA (0.51) | GLAPKMGAACYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7285685 | 0.99 | GLA (0.51) | GLAPKMGAACYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7277609 | 0.90 | GLA (0.57) | GLAPKMGAACYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7277624 | 0.90 | GLA (0.57) | GLAPKMGAACYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7287900 | 0.85 | GLA (0.59) | GLAPKMGAACYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7287909 | 0.85 | GLA (0.59) | GLAPKMGAACYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7284411 | 0.84 | GLA (0.49) | GLAPKMGAACYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7277753 | 0.77 | PKM (0.44) | PKMGAACYP2C19KMT2AF2 | |
| Hydrochloric Acid SCHEMBL7277734 | 0.77 | PKM (0.44) | PKMGAACYP2C19KMT2AF2 | |
| Hydrochloric Acid SCHEMBL7284414 | 0.76 | GLA (0.42) | GLAPKMGAACYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529858-B1 | 2-Piperazinone compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5294713-A | Inhibiting cell adhesion | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0529858-A1 | 2-Piperazinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |